Reinstate UI selection of liver function parameter on y-axis.
Convert mod_edish()lb_date_var to a mandatory argument removing the NULL default.
dv.edish 2.0.0
Refactor code to use {ggiraph} instead of {plotly}.
Move options from a sidebar layout to a drop menu.
For each subject, plot normalized peak TBILI against normalized peak ALT/AST values, with the option to plot aminotransferase values for each visit.
Implement spider/path lines when aminotransferase values plotted for each visit.
Apply log value to axes.
Mixing ULN for ALT/AST and baseline for TBILI (or vice versa) is not standard and generally does not make scientific sense in DILI analysis, but the previous eDISH plot allowed control of ULN/baseline for each axis. Update to use only one selector for ULN/baseline that applies to both axes.
Update tooltip/hover text:
Show the time between peaks.
Show the sequence (peak ALT/AST on or before peak TBILI most concerning).
Show value of ALP (Alkaline Phosphatase) at the time of peak ALT/AST value, flagged ≤ 2 x ULN or > 2 x ULN (or baseline).
dv.edish 1.3.0
Add jumping feature.
Arm default values can be arbitrarily specified as long as they are character strings. This supports including multiple studies with different arm values.
dv.edish 1.2.0
The user can now specify the x- and y-axis range limits, or go with the default plotly ranges.
dv.edish 1.1.0
Remove support for data dispatchers.
Split mod_edish()dataset_names parameter into subject-level and laboratory datasets.
Provide early feedback of mod_edish() misconfiguration.
dv.edish 1.0.4
The module ignores now NA values when calculating the maximum value.
dv.edish 1.0.3
Initial release of dv.edish package to GitHub.
dv.edish 1.0.2
The module is now able to deal with multiple values per subject, visit, and lab test by using the maximum value.
When there is no data to display, e.g., due to filter settings, the module will provide a meaningful output.
The module has been updated to show commonly used default values for reference lines. For the x-axis, the default value is 3, and for the y-axis, the default value is 2.
dv.edish 1.0.1
Bugfix: Bookmarking the app’s state failed for arm and parameter selection but is fixed now.