Modified ncar::pdfNCA to support watermarks
Usage
pdfNCA_wm(
fileName = "Temp-NCA.pdf",
concData,
key = "Subject",
colTime = "Time",
colConc = "conc",
dose = 0,
adm = "Extravascular",
dur = 0,
doseUnit = "mg",
timeUnit = "h",
concUnit = "ug/L",
down = "Linear",
R2ADJ = 0,
MW = 0,
SS = FALSE,
iAUC = "",
excludeDelta = 1,
watermark = TRUE,
internal_version = TRUE,
debug_msg = TRUE
)
Arguments
- fileName
file name to save
- concData
concentration data table
- key
column names of concData to be shown in the output table
- colTime
column name for time
- colConc
column name for concentration
- dose
administered dose
- adm
one of
"Bolus"
or"Infusion"
or"Extravascular"
to indicate drug administration mode- dur
duration of infusion
- doseUnit
unit of dose
- timeUnit
unit of time
- concUnit
unit of concentration
- down
either of
"Linear"
or"Log"
to indicate the way to calculate AUC and AUMC- R2ADJ
Minimum adjusted R-square value to determine terminal slope automatically
- MW
molecular weight of drug
- SS
if steady-state, this should be TRUE. AUCLST (AUClast) is used instead of AUCIFO (AUCinf) for the calculation of Vz (VZFO, VZO), CL (CLFO, CLO), and Vdss (VSSO).
- iAUC
interval AUC information in a dataframe with "Name", "Start", and "End" columns
- excludeDelta
Improvement of R2ADJ larger than this value could exclude the last point. Default value 1 is for the compatibility with other software. Author recommends to use
excludeDelta
option with about 0.3.- watermark
Insert watermark when TRUE
- internal_version
changes temp dir pathing as a workaround for cloud hosting where access rights prevent writing
- debug_msg
show debug messages