Spider plot functionality added for batch runs (#46)
MVPapp 0.3.1 (2025-06-12)
Bugfixes
Weight-based dosing now correctly apply for batch runs and variability simulations (#6)
MVPapp 0.3.0 (2025-06-09)
Features
Implemented Batch runs (Parameter Sensitivity Analysis Page - All Parameters) to assess all parameters in the model with a defined upper/lower range in a single click (#44)
QoL features includes fixing parameters, reset entire table, multiple display scales, and other graphical options
Bugfixes
General performance improvements for larger models with long sampling (#43)
Stability and minor UI fixes
MVPapp 0.2.19 (2025-06-03)
Features
Re-worked median line bins to be based on quantiles (#37, #38)
Built-in data filtering option to distinct by ID (#40)
More QoL options for NCA (safeguards and rounding) (#41)
Minor re-factoring and other QoL updates
Bugfixes
Prevent non-sensible parameter estimates from crashing the entire app (#42)
Bug fixes for General Plot’s box plot count labels (#39)
Better handling of NAs for Quantize X-axis option in General Plot
MVPapp 0.2.18 (2025-04-21)
Features
New option for individual plots to identify outliers (#36)
New option for individual plots to sort by one or more variables (#35)
Additional tooltips for several options
Separate plot titles for general and individual plots
New template model (Parallel zero/first-order absorption model)
Bugfixes
Fixed a bug where NCA would fail if dosing rows are not excluded by default (#33)
Safeguard for simulating too many samples, with a default value of max 20000 samples (#32)
NCA is now sorted by the grouping variable, followed by the dose column (#34)
MVPapp 0.2.17 (2025-03-13)
Features
New option to split X-axis into quantiles for Data Page General Plots (#30)
More template models (QS TMDD, MM TMDD).
Bugfixes
Allows age and/or weight range sliders in Variability page to be the same value (#29)
Re-worded some tooltips to improve clarity.
MVPapp 0.2.16 (2025-03-04)
Features
Implement a short delay for some inputs to avoid frequent computations (#28)
Progress bars for longer computations where a spinner graphic is not feasible (#16)
Bugfixes
Allow “Total Doses” for each Dosing Regimen to be 0 (#14)
MVPapp 0.2.11 (2024-12-04)
Features
Support for uploading tab-delimited .txt files on Data Upload, with the option to automatically create ID column. (#9)
Uses dose column instead of manually entering dose amount for NCA.
Download Options now support non-interactive plots, with a dedicated “Download Non-Interactive Plot” button. (#11)
Bugfixes
NCA Clearance unit corrected to be based on the supplied time unit.
Linear regression is center aligned for ggplots (#10)
MVPapp 0.2.10 (2024-11-28)
Features
Less strict requirements for Data Exploration plots to only require “ID” column to be present (previously would require “ID”, “DV”, and “TIME”).
Interactive plot toggle for Simulation and Data page plots.
Boxplot functionality for Data Exploration - Plot Output. (#7)
Text size option for labels (affects linear regression formulae and boxplot counts (N=x) only).
Bugfixes
Fixed some typos.
Most selectizeInputs now sort alphabetically.
Other
Suggests mrgsolve v.1.5.2 to be installed.
MVPapp 0.2.9 (2024-10-25)
Features
Upgraded Data Input - Plot Output tab, supporting facets, smoothers, and linear regression. (#5)
Bugfixes
Fixed display error when model does not compile for PSA plots. (#2)
Fixed wrong behavior for median lines binning. (#4)
Consistently include dates for all downloadable items.
MVPapp 0.2.8 (2024-10-14)
Features
More template models (1 CMT lag time).
Increasing default decimal places (3 -> 5) for variability quantiles.
Supports $PRED syntax. When model has $PRED syntax, dosing amounts will be disabled.
Using recover = TRUE by default to output more helpful error messages when mrgsolve does not compile.
Bugfixes
Bugfix for WT-based dosing to propagate correctly to Parameter Sensitivity Analysis when WT is a parameter (Note: currently WT-based dosing remains unsupported in Variability simulations).